Add-ons & Analytical methods

Acquire background information on the add-on concept and learn how to use the analytical methods provided by PLA 3.0 add-ons.


Working with add-ons

Employ the 'Add-on management' feature to manage your add-ons from within PLA 3.0. Activate the add-ons you want to use and add sample documents and templates.

Request trial versions or quotes for add-ons not yet included in your license or deactivate add-ons you no longer require. Get an overview of available upgrades and migrate to a higher add-on version with just a few clicks. For more details, please consult the »How-to Guide« Working with add-ons.


Analyzing data

PLA 3.0 supports a wide variety of methods for biostatistical analysis. To access a method, activate the respective add-on in your PLA 3.0 system, and start to develop your assay using the provided document types.

The following commercial off-the-shelf add-ons provide analytical methods:

Biological Assay Package: The Biological Assay Package add-on organizes data, processes, and results in documents. It provides various document types that broadly correspond to the functional areas of assay documents, advanced calculations, and supporting documents. For details, please go to Biological Assay Package.

Control Chart Package: The Control Chart Package allows sophisticated statistical process control (for example, by plotting Shewhart I-Charts as recommended in the USP <1010>) and also provides a set of visualization options to fine-tune your statistical process control mechanisms. For details, please go to Control Chart Package.

Dichotomous Assay Package: Use the Dichotomous Assay Package to set up quantal response assays or binary assays. Calculate relative potencies of Test samples based on binary input values, such as the fraction of specimen that exhibits one of two possible responses. For details, please go to Dichotomous Assay Package.

Dose-Response Analysis Package: The Dose-Response Analysis Package provides various biostatistical methods for immunoassays, ELISA, and more. It supports you in investigating equivalence for calibration curves, provides enhanced data processing, and options for subgroup analysis. For details, please go to Dose-Response Analysis Package.

Microbial Assays for Antibiotics Package: The Microbial Assays for Antibiotics Package supports various methods, that is, cylinder-plate, turbidimetric, and combination of microbial assays. It enables you to closely follow the guidelines laid out in the United States Pharmacopeia (USP <81>) and the Japanese Pharmacopoeia (JP 4.02). For details, please go to Microbial Assays for Antibiotics Package.


Acquiring data

Use our Data Acquisition Module add-ons to acquire data from your instruments. Each Data Acquisition Module is specific to the external data format it supports.

The following add-ons provide data acquisition functionality:

Cytiva Biacore™
Acquire data from Cytiva Biacore™ Control Software. Supports XML files. For details, please consult the User Guide (version: 1.1.0).

Gen5™
Acquire data from BioTek Gen5™. Supports XPT files. Requires an installed Gen5™ system. For details, please consult the User Guide (version: 1.3.0).

Microsoft Excel®
Acquire data from Microsoft Excel®. Supports XSL and XSLX files. For details, please consult the User Guide (version: 1.2.0).

SoftMax® Pro (3x. - 5.x)
Acquire data from Molecular Devices' Softmax® Pro 3.x - 5.x. Supports PDA and EDA files. For details, please consult the User Guide (version: 1.7.0).

SoftMax® Pro (6.x - 7.x)
Acquire data from Molecular Devices' Softmax® Pro 6.x - 7.x. Supports XML files. For details, please consult the User Guide (version: 1.7.0).

SoftMax® Pro (6.x - 7.x) for digitally signed data
Acquire data from Molecular Devices' Softmax® Pro 6.x - 7.x. Supports XML files with digital signatures only. For details, please consult the User Guide (version: 1.7.0).

Tecan Magellan™
Acquire data from Tecan Magellan™. Supports WSP files. For details, please consult the User Guide (version: 1.3.1).

Tecan Magellan™ Automation
Acquire data from Tecan Magellan™. Supports WSP and MTH files. Makes use of the automation interfaces and requires an installed Tecan Magellan™ system. For details, please consult the User Guide (version: 1.3.1).

Text
Acquire data from text files. Powerful configuration options support all common structured text formats. For details, please consult the User Guide (version: 1.2.0).

Use our Document Import Module add-ons to generate fully specified documents of a specific type. The following add-on provides data import functionality:

Bio-Plex®
Import measured values of Bio-Plex® files into the dataset. For details, please consult the User Guide (version: 1.2.0).


Supporting add-ons

We provide a range of add-ons you can use, for example, to speed up your daily processes, migrate your data from an earlier PLA version, or export data from PLA 3.0 to another system.

The following tools are available as commercial off-the-shelf add-ons:

Integration Report Package: Use the Integration Report Package to export results from Quantitative response assay documents and Combination of assay results documents into file formats such as CSV, INI, and XML. For details, please go to Integration Report Package.

PLA 3.0 Migration and Archiving Toolkit: Use our Migration and Archiving Toolkit to migrate your 2.x databases to a PLA 3.0 environment. For details, please go to PLA 3.0 Migration and Archiving Toolkit.

Biological Assay Simulation Package (Technology Preview): Use this add-on to create simulated assays containing artificial data and gain new insights into the behavior of your existing assays. For details, please go to Biological Assay Simulation Package.

Split Assay Package: Use our Split Assay Package to split Quantitative response assays with more than one Test sample into their respective 1-on-1 assays. For details, please go to Split Assay Package.

Measurement Documentation: The Measurement Documentation add-on allows you to document different aspects of your measurement in a central place, and link the information to the related assay documents. For details, please go to Measurement Documentation.

Generic Document Types: Use the Generic Document Types add-on to document general information. For details, please go to Generic Document Types.